How therapeutic ketosis and metabolic flexibility support energy, healing, and hormone harmony
By Angela Di Serio, Nutritional Medicine Practitioner

We’ve been told for decades that fat is the enemy.

We were told it clogs arteries, makes us gain weight, and should be feared in favor of “heart-healthy” whole grains and low-fat everything.

But here’s what the science — and my clinical experience — tells us now:
Your body was designed to thrive on fat.
Not just survive — thrive.

And when you become fat adapted, your metabolism unlocks a state of clarity, healing, and resilience that most people never get to experience in our sugar-fueled world.

Let me explain.

What does it mean to be fat adapted?

Being fat adapted means your body has learned how to efficiently burn fat for fuel, instead of constantly relying on glucose (sugar and carbs). When you’re fat adapted, you can go longer between meals without crashing. Your brain feels sharper. Your energy is more stable. Your cravings diminish.

But more importantly?

Your body starts to heal.

When we tap into our fat-burning pathways — especially through tools like therapeutic ketosis — we lower inflammation, reduce insulin resistance, and give our mitochondria (the energy powerhouses of our cells) a serious upgrade.

Why this matters — especially for women

Here’s what I see all the time:
Women come to me exhausted, inflamed, bloated, and emotionally disconnected from their bodies. They’ve tried every diet, every cleanse, and nothing feels sustainable.

What they don’t realize is that their metabolism is stuck in sugar-burning mode, constantly spiking and crashing — and taking their hormones, mood, and energy levels down with it.

When we shift into a fat-adapted state, everything begins to recalibrate.

Appetite normalizes. Mental fog lifts. Cycles regulate.
And most importantly — you begin to trust your body again.

What about ketosis?

Ketosis is a metabolic state where your body uses ketones (made from fat) as its primary fuel source. It’s powerful when used therapeutically — especially for conditions like:

• Blood sugar dysregulation

• Neurological conditions

• PCOS and hormonal imbalance

• Chronic inflammation

• Post-cancer recovery

• Weight plateaus despite clean eating

But it’s not about guzzling bacon and cheese.
The way I approach ketosis is clean, intentional, and nutrient-dense — rooted in whole foods, metabolic cycles, and your body’s natural rhythms.

The real power: metabolic flexibility

Being fat adapted isn’t about staying in ketosis forever.
It’s about having metabolic flexibility — the ability to seamlessly shift between fat and glucose as needed. This is where my Feast & Famine method comes in: cyclical eating patterns that align with ancient wisdom, modern science, and your body’s seasons.

We feast. We fast. We nourish deeply. And we listen.

This isn’t a fad — it’s a return to what’s always been true.

Your body knows how to heal.
Your metabolism isn’t broken — it’s just been confused.
When we remove the processed food noise and give your body the right fuel, everything begins to change.

Not just your weight.
Not just your lab results.
But your relationship with yourself.

Ready to explore therapeutic ketosis or get support on becoming fat adapted?
Let’s create a plan rooted in nature, backed by science, and tailored to you.

[→ Learn About the Feast & Famine Program]
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